MOTS-c 10mg - 99.62%
$110.00
MOTS-c: The Mitochondrial Signaling Peptide
- Products will arrive in a lyophilized (powder) form for maximum stability.
MOTS-c is a 16–amino-acid mitochondrial-derived peptide (MDP) that acts as a key regulator of cellular energy homeostasis. Synthesized in mitochondria, MOTS-c translocates to the nucleus under metabolic stress, modulating transcription of genes involved in mitochondrial biogenesis, oxidative phosphorylation, and metabolic adaptation. Mechanistically, it activates the AMPK pathway to enhance cellular energy efficiency, influences SIRT1 signaling for stress resistance, and engages NRF2-mediated antioxidant responses. MOTS-c has been extensively studied in the context of glucose and lipid metabolism, insulin sensitivity, and mitochondrial resilience, positioning it as a focal point in research on exercise physiology, metabolic regulation, and age-associated cellular stress.
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